The relationship between the symptoms of female gonococcal infections and serum progesterone level and the genotypes of Neisseria gonorrhoeae multi-antigen sequence type (NG-MAST) in Wuhan, China

• DOI: 10.1007/s10096-010-1040-x
• Publication Date: 2010-09-03T07:26:04Z
• Authors: Z. Wu; L. Xu; Y. Tu; R. Chen; Y. Yu; J. Li; M. Tan; H. Chen
• Keywords: Neisseria gonorrhoeae; Medical microbiology

The objective of this investigation was to study the relationship between symptoms female gonococcal infections and serum progesterone level genotypes Neisseria gonorrhoeae multi-antigen sequence type (NG-MAST) in Wuhan, China. Eighty-one strains N. were harvested from vaginal discharge 975 adult females Wuhan genotyped by using NG-MAST. Serum (P) estradiol (E2) levels measured radio immunoassay (RIA) 39 gonorrhea-infected patients with slight (asymptomatic group) 42 conspicuous (symptomatic group). average asymptomatic group significantly higher than symptomatic (p < 0.05), while no significant difference found two groups. Of 81 wild-type isolates, 50 NG-MAST types associated ST2951, ST735, ST436 principally patients. ST809 ST369, however, mainly detected subjects. Gonococcal genetic island (GGI)-positive GGI-negative both group. In infection, high is absence symptoms, but association revealed presence symptoms. GGI bears relation