Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis

• DOI: 10.1007/s10143-024-02527-5
• Publication Date: 2024-07-31T10:02:01Z
• Authors: Basel Musmar; Hamza Adel Salim; Nimer Adeeb; Assala Aslan; Bahaa Aljeradat; Jose Danilo Bengz...; Rachel M. McLellan; Oktay Algin; Sherief Ghozy; Mahmoud Dibas; Sovann V. Lay; Adrien Guenego; Leonardo Renieri; Nicole M. Cancell...; Joseph Carnevale; Guillaume Saliou; Panagiotis Mastor...; Kareem El Naamani; Eimad Shotar; Kevin Premat; Markus Möhlenbruch; Michael Kral; Justin E. Vranic; Charlotte Chung; Mohamed M. Salem; Ivan Lylyk; Paul M. Foreman; Jay A. Vachhani; Hamza Shaikh; Vedran Župančić; Muhammad U. Hafeez; Joshua Catapano; Muhammad Waqas; Vincent M. Tutino; Mohamed K. Ibrahim; Marwa A. Mohammed; M. Ozgur Ozates; Giyas Ayberk; James D. Rabinov; Yifan Ren; Clemens M. Schirmer; Mariangela Piano; Anna L. Kühn; Caterina Michelozzi; Stéphanie Elens; Robert M. Starke; Ameer Hassan; Mark Ogilvie; Anh Nguyen; Jesse Jones; Waleed Brinjikji; Marie T. Nawka; Marios Psychogios; Christian Ulfert; Julian Spears; Brian T. Jankowitz; Jan-Karl Burkhardt; Ricardo A. Domingo; Thien Huynh; Juan Carlos Marti...; Muhammed Amir Ess...; Sunil A. Sheth; Gary Spiegel; Rabih Tawk; Boris Lubicz; Pietro Panni; Ajit S. Puri; Guglielmo Pero; Erez Nossek; Eytan Raz; Monika Killer-Obe...; Christoph J. Grie...; Hamed Asadi; Adnan Siddiqui; Allan Brook; David Altschul; Andrew F. Ducruet; Felipe C. Albuque...; Robert W. Regenhardt; Christopher J. St...; Peter Kan; Vladimir Kalousek; Pedro Lylyk; Srikanth Boddu; Jared Knopman; Mohammad A. Aziz-...; Stavropoula I. Tj...; Frédéric Clarençon; Nicola Limbucci; Hugo H. Cuellar-S...; Pascal M. Jabbour; Vitor Mendes Pereira; Aman B. Patel; Adam A. Dmytriw
• Keywords: Male; Adult; Research; Endovascular Procedures; Intracranial Aneurysm; Middle Aged; Embolization, Therapeutic; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Humans; Intracranial Aneurysm/therapy; Intracranial Aneurysm/surgery; Male; Propensity Score; Female; Middle Aged; Retrospective Studies; Aged; Endovascular Procedures/methods; Treatment Outcome; Adult; Embolization, Therapeutic/methods; Aneurysms; Intracranial; Treatment; WEB; Woven EndoBridge; Humans; Female; Propensity Score; Retrospective Studies; Aged

Abstract The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB in versus small . conducted a retrospective review WorldWide Consortium database, from 2011 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed compare baseline characteristics. A total 898 patients were included. There no significant difference observed presentations, smoking status, pretreatment mRS, presence multiple aneurysms, location, or prior treatment between two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) higher retreatment (12% 3.6%, < 0.001) aneurysm group. These findings may inform decisions patient counseling. Future studies are needed further explore this area.