Prognostic value of hematological parameters in patients undergoing esophagectomy for esophageal squamous cell carcinoma

• DOI: 10.1007/s10147-016-0986-9
• Publication Date: 2016-05-06T10:07:40Z
• Authors: Noriyuki Hirahara; Takeshi Matsubara; Daisuke Kawahara; Yoko Mizota; Shuichi Ishibashi; Yoshitsugu Tajima
• Keywords: Esophagectomy; Surgical oncology; Univariate analysis; Mean platelet volume

It is now widely recognized that outcomes in cancer patients are not determined by their tumor characteristics alone. In this study, we retrospectively analyzed the clinical data of esophageal to evaluate impact red blood cell distribution width (RDW), platelet (PDW), and mean volume (MPV) on cancer-specific survival (CSS). We reviewed a database 144 consecutive who underwent curative esophagectomy for squamous carcinoma at our institute between 2006 2014. multivariate analysis, pathological stage (pStage) (p = 0.0002) high RDW 0.0300) were found be independently associated with poor survival. Patients had significantly poorer prognosis terms CSS than those low 0.004). Among non-elderly patients, analysis demonstrated pStage 0.0120), 0.0092) independent risk factors worse prognosis. addition, 0.0003). On other hand, univariate 0.0008) was only significant factor elderly patients. confirmed after esophagectomy. Furthermore, predictor