Botulinum toxin: could it be an effective treatment for chronic tension-type headache?

• DOI: 10.1007/s10194-008-0082-2
• Publication Date: 2008-11-21T15:08:22Z
• Authors: Sherif M. Hamdy; Hatem Samir; M. El-Sayed; Nermin Adel; Rasha Hasan
• Keywords: Adult; Male; Botulinum Toxins; Original; Tension-Type Headache; Clinical Neurology; Analgesics, Non-Narcotic; Middle Aged; Injections, Intramuscular; Severity of Illness Index; 3. Good health; 03 medical and health sciences; Anesthesiology and Pain Medicine; Treatment Outcome; 0302 clinical medicine; Chronic Disease; Humans; Egypt; Female; Single-Blind Method

Several clinical trials suggest that botulinum toxin type-A (BTX-A) may be an effective treatment option for patients with chronic tension-type headache (CTTH); however, controversy remains as to how the optimally should used treating and which patient's profile fits this treatment. The objective of study was evaluate efficacy tolerability BTX-A prophylactic CCTH in Egyptian patients. This a randomized, single-blind, placebo-controlled aged 25–50 years old CCTH. Following 30-day screening, parameters severity assessed by standard visual analogue scale (VAS), 25-item Henry Ford Hospital Headache Disability Inventory (HDI) were recorded baseline. Then, injection done either or saline combination two methods detecting sites (the fixed-site approach follow-the-pain approach). Our showed significant improvement after 1 month regarding days/month, measured VAS HDI severity. There reduction medications, there minor complications, but these reversed spontaneously without further well-tolerated