Role of cardiovascular magnetic resonance end-systolic 3D-SSFP sequence in repaired tetralogy of Fallot patients eligible for transcatheter pulmonary valve implantation

• DOI: 10.1007/s10554-019-01630-9
• Publication Date: 2019-06-03T08:02:53Z
• Authors: Benedetta Leonardi; Aurelio Secinaro; Marco Alfonso Per...; Davide Curione; Carmela Napolitano; Maria Giulia Gagl...
• Keywords: Balloon Valvuloplasty; Male; Cardiac Catheterization; Pulmonary Circulation; 3D-SSFP navigator sequence; Adolescent; Clinical Decision-Making; 610; Magnetic Resonance Imaging, Cine; Prosthesis Design; Settore MED/11; 03 medical and health sciences; 0302 clinical medicine; Percutaneous pulmonary valve; Predictive Value of Tests; Image Interpretation, Computer-Assisted; Humans; Cardiac Surgical Procedures; Child; Heart Valve Prosthesis Implantation; Observer Variation; Patient Selection; Hemodynamics; Pulmonary Valve Insufficiency; 3. Good health; Heart Valve Prosthesis; Tetralogy of Fallot; Cardiovascular magnetic resonance; Female

To evaluate the usefulness of cardiovascular magnetic resonance (CMR) 3D steady state free precession (SSFP) sequence acquired at end-systole (ES) in repaired Tetralogy of Fallot (rToF) patients eligible for percutaneous pulmonary valve implantation (PPVI). Between 2012 and 2018, 78 rToF patients were selected for pulmonary valve replacement (PVR) according to CMR criteria. CMR protocol included 3D-SSFP sequence used to assess the right ventricle outflow tract (RVOT) diameters at three levels (pulmonary valve remnant, mid-portion, bifurcation) in mid-diastole (MD) or ES, RVOT length and coronary artery anatomy. In 20 rToF patients without indications for PVR (controls), 3D SSFP sequence was acquired at both cardiac phases (MD and ES) to evaluate RVOT dimension throughout the cardiac cycle. Invasive balloon sizing was recorded in patients undergoing PPVI. The 3D-SSFP sequence was performed in MD on 39 patients and in ES on other 39, of whom 26 patients met the criteria for PPVI. The latter was unsuccessful in ten patients (38%), mainly due (80% of cases) to significant size discrepancy at PV remnant and bifurcation levels (p = 0.019 and 0.037 respectively) between the measurements by 3D-SSFP in MD and those by the balloon size in systole. Significant RVOT size difference between MD and ES was present at mid-portion and bifurcation levels in the PVR candidate group, and at all three-levels in the control group (all p < 0.001). ES 3D-SSFP sequence is able to quantify RVOT dilation in rToF patients at its maximum expansion, thus improving selection of PPVI candidates.