Former uranium mine-induced effects in caged roach: a multiparametric approach for the evaluation of in situ metal toxicity

• DOI: 10.1007/s10646-014-1374-8
• Publication Date: 2014-10-27T07:49:59Z
• Authors: Béatrice Gagnaire; Anne Bado-Nilles; Stéphane Betoulle; Rachid Amara; Virginie Camilleri; Isabelle Cavalié; Edith Chadili; Laurence Delahaut; Elodie Kerambrun; Daniel Orjollet; Olivier Palluel; Wilfried Sanchez
• Keywords: Male; Geologic Sediments; 550; Roach; Cyprinidae; Risk Assessment; 01 natural sciences; Mining; Animals; 0105 earth and related environmental sciences; [SDV.TOX.ECO] Life Sciences [q-bio]/Toxicology/Ecotoxicology; Environmental risk assessment; Bioaccumulation; 6. Clean water; Oxidative Stress; Metals; 13. Climate action; Uranium; Rutilus rutilus; Female; [SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology; France; Uranium mining releases; Biomarkers; Water Pollutants, Chemical; Environmental Monitoring

To characterize environmental risks linked to former uranium mines in the Limousin region of France, a study was conducted on fish health effects from uranium releases. Two private ponds were compared in this study, one with uranium contamination and one background site, upstream of the mining zone. Roach, Rutilus rutilus, were caged for 28 days in both ponds. Physico-chemical parameters of water and sediments and bioaccumulation of metals in several organs were determined. After 14 and 28 days of caging, immune, oxidative stress, biotransformation, neurotoxicity and physiological parameters were measured. Iron and aluminium were quantified in the water of both sites; however, barium and manganese were only present in the water of the uranium contaminated site. Uranium was present in both sites but at very different concentrations. The sediments from the uranium contaminated site contained high levels of radioactive elements coming from the disintegration chain of uranium. Results of biological parameters indicated stimulation of immune parameters and of oxidative stress and a decrease of AChE in fish caged in the uranium contaminated pond compared to the uranium-free pond. Overall, the results determined roach health status in the context of pollution from poly-metallic mining. The data strengthen our knowledge of the environmental risk assessment associated with radioactive substances in the environment.