Comprehensive analysis of codon usage pattern in Withania somnifera and its associated pathogens: Meloidogyne incognita and Alternaria alternata

• DOI: 10.1007/s10709-022-00154-w
• Publication Date: 2022-04-13T16:03:19Z
• Authors: Jyoti Chandan; Suruchi Gupta; Vikash Babu; Deepika Singh; Ravail Singh
• Keywords: 0301 basic medicine; Original Paper; 03 medical and health sciences; Alternaria; Animals; Tylenchoidea; Withania; Codon Usage

Meloidogyne incognita (Root-knot nematode) and Alternaria alternata (fungus) were among the dominant parasites of medicinal plant Withania somnifera. Despite fatal nature their infection, a comprehensive study to explore evolution adaptation is lacking. The present elucidates evolutionary codon usage bias analysis W. somnifera (host plant), M. (root-knot A. (fungal parasite). results revealed weak prevalent in all three organisms. Based on nucleotide analysis, genome was found be A-T biased while had GC genome. We high similarity CUB pattern between host its nematode pathogen as compared fungal pathogen. Inclusively, both forces influenced associated pathogens. However, neutrality plot indicated pervasiveness natural selection Correspondence effect mutation main force affecting alternata. Taken together would provide some prolific insight into role adaptability pathogens host's environment for establishing parasitic relationship.