What is the clinical impact of the endometrial receptivity array in PGT-A and oocyte donation cycles?

• DOI: 10.1007/s10815-019-01535-5
• Publication Date: 2019-07-27T06:02:21Z
• Authors: Ana Raquel Neves; Marta Devesa; Francisca Martínez; Sandra Garcia-Mar...; Ignacio Rodriguez; Nikolaos P. Polyzos; Buenaventura Coroleu
• Keywords: Adult; 0301 basic medicine; Pregnancy Rate; Implantation failure; Fertilization in Vitro; Endometrium; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Humans; Embryo Implantation; Treatment Failure; Preimplantation Diagnosis; Endometrial receptivity array; Retrospective Studies; Oocyte Donation; Oocyte donation; Pregnancy Outcome; Middle Aged; Aneuploidy; Blastocyst; Female; PGT-A

(Abstracted from J Assist Reprod Genet 2019;36:1901–1908) Endometrial receptivity is a critical factor to likelihood of implantation after embryonic transfer (ET), yet potential biomarkers for receptivity have thus far failed at reliably predicting clinical pregnancy. Recent evidence has suggested that the Endometrial Receptivity Analysis (ERA), a microarray-based test to evaluate endometrial gene expression, may be valuable in prediction of endometrial receptivity and recommendation of endometrial preparation before ET.