Superparamagnetic MFe2O4 (M = Ni, Co, Zn, Mn) nanoparticles: synthesis, characterization, induction heating and cell viability studies for cancer hyperthermia applications

• DOI: 10.1007/s10856-015-5466-7
• Publication Date: 2015-02-17T12:44:13Z
• Authors: Sandip Sabale; Vidhya Jadhav; Vishwajeet Khot; Xiaoli Zhu; Meiling Xin; Hongxia Chen
• Keywords: Superparamagnetism; Magnetic hyperthermia; Viability assay; Induction Heating; Hyperthermia therapy

Superparamagnetic nanoferrites are prepared by simple and one step refluxing in polyol synthesis. The ferrite nanoparticles prepared by this method exhibit particle sizes below 10 nm and high degree of crystallinity. These ferrite nanoparticles are compared by means of their magnetic properties, induction heating and cell viability studies for its application in magnetic fluid hyperthermia. Out of all studied nanoparticles in present work, only ZnFe2O4 and CoFe2O4 MNPs are able to produce threshold hyperthermia temperature. This rise in temperature is discussed in detail in view of their magneto-structural properties. Therefore ZnFe2O4 and CoFe2O4 MNPs with improved stability, magnetic induction heating and cell viability are suitable candidates for magnetic hyperthermia.