Evaluation of the Integrated Pulmonary Index® during non-anesthesiologist sedation for percutaneous endoscopic gastrostomy

• DOI: 10.1007/s10877-020-00563-2
• Publication Date: 2020-07-30T08:03:46Z
• Authors: Florian Alexander...; Jan Peveling-Oberhag; Eva Herrmann; Stefan Zeuzem; Jörg Bojunga; Mireen Friedrich-...
• Keywords: Capnography; Pulse Oximetry; Respiratory Rate; Oxygen Saturation

Standard monitoring of heart rate, blood pressure and arterial oxygen saturation during endoscopy is recommended by current guidelines on procedural sedation. A number studies indicated a reduction hypoxic (art. oxygenation < 90% for > 15 s) severe events 85%) additional use capnography. Therefore, U.S. the European comment that capnography can be considered in long or deep Integrated Pulmonary Index® (IPI) an algorithm-based parameter combines measured pulse oximetry oxygenation, rate) ventilation (respiratory apnea 10 s, partial end-tidal carbon dioxide [PetCO2]). The aim this paper was to analyze value IPI as monitor respiratory status patients receiving propofol sedation PEG-procedure. Patients reporting PEG-placement under were randomized 1:1 either standard group (SM) including (IM). Heart monitored SM. In IM performed measuring PetCO2, rate IPI. Capnography values recorded all but only visible endoscopic team IM-group. range between 1 (10 = normal; 8-9 within normal range; 7 close range, requires attention; 5-6 attention may require intervention; 3-4 1-2 immediate intervention). Results versus same study population published previously. total 147 (74 SM 73 IM) included present study. Hypoxic occurred 62 (42%) 44 (29%), respectively. Baseline characteristics equally distributed both groups. 1, well parameters PetCO2 0 mmHg s had high sensitivity events, respectively (IPI 1: 81%/81% [hypoxic/severe event], 7: 82%/88%, PetCO2: 69%/68%, s: 84%/84%). All four low specificity 13%/12%, 7%/7%, 29%/27%, 7%/7%). multivariate analysis, independent risk factors hypoxia. 7) individual allow fast convenient conclusion patients' morbid patient population. Sensitivity good most parameters, poor. conclusion, useful metric assess propofol-sedation PEG-placement. However, not superior s.