One-pot synthesis of 4-arylquinolines from aromatic aminoketones and vinylphosphonium salts

• DOI: 10.1007/s11030-009-9188-y
• Publication Date: 2009-08-12T05:42:41Z
• Authors: Sakineh Asghari; Mohammad Qandalee; Zahra Naderi; Zahra Sobhaninia
• Keywords: Vinyl Compounds; Chemistry, Organic; Quinolines; Salts; Amines; Ketones; Hydrocarbons, Aromatic; 01 natural sciences; 0104 chemical sciences

The addition of acetylenic esters to aromatic amines such as 2-amino benzophenone derivatives in the presence of triphenylphosphine leads to highly functionalized phosphoranes, which undergo an intramolecular Wittig reaction following oxidation to produce quinoline derivatives.