Synthesis and pharmacological activity of aroylmethyl derivatives of tricyclic benzimidazole systems containing hydroxy groups in aroyl radicals

• DOI: 10.1007/s11094-007-0028-z
• Publication Date: 2007-10-05T15:00:53Z
• Authors: V. A. Anisimova; I. E. Tolpygin; A. A. Spasov; V. A. Kosolapov; A. V. Stepanov; A. A. Orlova; L. V. Naumenko
• Keywords: Benzimidazole; Tricyclic

The synthesis and pharmacological properties of a series of aroylmethyl derivatives of tricyclic benzimidazole systems containing hydroxy groups in aroyl radicals are described. It is established that most of the synthesized compounds exhibit a high antioxidant activity, possess pronounced hemorheological properties, and influence the blood glucose level.