Ferredoxin: the central hub connecting photosystem I to cellular metabolism

• DOI: 10.1007/s11099-018-0793-9
• Publication Date: 2018-02-28T04:06:30Z
• Authors: J. Mondal; B. D. Bruce
• Keywords: Hydrogenase; Sulfite reductase; Iron–sulfur cluster; Sulfur Metabolism; Trichodesmium

Ferredoxin (Fd) is a small soluble iron-sulfur protein essential in almost all oxygenic photosynthetic organisms. It contains single [2Fe-2S] cluster coordinated by four cysteine ligands. accepts electrons from the stromal surface of PSI and facilitates transfer to myriad acceptors involved diverse metabolic processes, including generation NADPH via Fd-NADP-reductase, cyclic electron transport for ATP synthesis, nitrate reduction, nitrite reductase, sulfite hydrogenase other reductive reactions. Fd serves as central hub these cellular reactions integral complex networks. We describe advances on role its evolutionary cyanobacteria algae/plants. compare structural diversity partners understand this orchestrating shed light how dynamically partitions between competing partner proteins enable optimum PSI-derived support cell growth metabolism.