Reliability, Validity and Responsiveness of the EQ-5D-5L in Assessing and Valuing Health Status in Adolescents and Young Adults with Posttraumatic Stress Disorder: a Randomized Controlled Trail

• DOI: 10.1007/s11126-020-09814-6
• Publication Date: 2020-08-17T08:03:57Z
• Authors: Judith Dams; Eline Rimane; Regina Steil; Babette Renneberg; Rita Rosner; Hans-Helmut König
• Keywords: Male; Adolescent; Psychometrics; Health Status; 150; 610; Validity; Stress Disorders, Post-Traumatic; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Surveys and Questionnaires; EQ5D; Humans; Surveys and Questionnaires [MeSH] ; Adolescent [MeSH] ; Female [MeSH] ; Validity ; Health Status [MeSH] ; Posttraumatic stress disorder ; Humans [MeSH] ; Stress Disorders, Post-Traumatic/psychology [MeSH] ; Stress Disorders, Post-Traumatic/diagnosis [MeSH] ; Responsiveness ; EQ5D ; Male [MeSH] ; Reproducibility of Results [MeSH] ; Psychometrics/standards [MeSH] ; Quality of Life [MeSH] ; Original Paper ; Young Adult [MeSH] ; Reliability; 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie; Original Paper; Reproducibility of Results; Posttraumatic stress disorder; Responsiveness; 100; Reliability; 16. Peace & justice; 3. Good health; Quality of Life; Female

To validate the EQ-5D-5L health-related quality of life (HrQoL) questionnaire in adolescents and young adults with posttraumatic stress disorder (PTSD) after sexual and/or physical abuse. We used data from a randomized controlled trial 87 participants PTSD aged 14-21 years. The discriminative ability was evaluated by comparing scores on descriptive system general population scores. Furthermore, between subgroups different disease severity levels estimated. Correlations EQ-5D index clinical parameters were to measure construct validity. Test-retest reliability measured intraclass correlation coefficients (ICC) baseline, posttreatment 3-month follow-up stable symptoms. Finally, responsiveness calculated mean differences, effect sizes receiver operating characteristic (ROC) analyses for improved Participants reported significantly more problems dimensions "mobility", "usual activities", "pain/discomfort" "anxiety/depression" than population. able discriminate levels. scales correlated absolute values varying 0.21 0.59. ICCs 0.65 0.91 indicated good test-retest index. EQ-VAS baseline follow-up, statistically significant 0.71 0.87, respectively, whereas ICC 0.08 not significant. Effect ranged -0.008 0.40 - 0.32 EQ-VAS. area under curve ROC 0.64 0.60 0.70 Discriminative ability, validity good, rather weak. Nevertheless, can be HrQoL PTSD. German Clinical Trials Register identifier: DRKS00004787; date registration: 18th March 2013; https://www.drks.de.