Spiro indane-based phosphine–oxazoline ligands for palladium-catalyzed asymmetric arylation of cyclic N-sulfonyl imines

• DOI: 10.1007/s11243-019-00329-z
• Publication Date: 2019-04-30T04:55:27Z
• Authors: Zhongxuan Qiu; Yanshun Li; Zhenqing Zhang; Dawei Teng
• Keywords: Indane; Oxazoline; Stereocenter; Sulfonyl; Organometallic Chemistry; Dibenzofuran

Palladium complexes of indane-based phosphine–oxazoline ligands with a spirocarbon stereogenic center were examined for asymmetric addition of arylboronic acids to cyclic N-sulfonyl imines. Excellent reaction activities (up to 99% yield) and enantioselectivities (up to 99% ee) were obtained with a broad scope of substrate.