Metallophytes for organic synthesis: towards new bio-based selective protection/deprotection procedures

• DOI: 10.1007/s11356-014-3526-z
• Publication Date: 2014-09-16T03:22:26Z
• Authors: Claire M. Grison; Alicia Velati; Vincent Escande; Claude Grison
• Keywords: Protecting group; Organic Synthesis; Environmentally Friendly

We propose for the first time using metal hyperaccumulating plants for the construction of a repertoire of protection and deprotection conditions in a concept of orthogonal sets. Protection of alcohol, carbonyl, carboxyl, and amino groups are considered. The ecocatalysts derived from metal-rich plants allow selective, mild, eco-friendly, and efficient protection or deprotection reactions. The selectivity is controlled by the choice of the metal, which is hyperaccumulated by the metallophyte.