Environmental and biological monitoring of occupational formaldehyde exposure resulting from the use of products for hair straightening

• DOI: 10.1007/s11356-015-5343-4
• Publication Date: 2015-09-08T22:31:54Z
• Authors: Giovana Piva Peteffi; Marina Venzon Ant...; Caroline Carrer; Eduarda Trevizani...; Sílvia Santos; Jéssica Glaeser; Larissa Mattos; Luciano Basso da ...; Rafael Linden
• Keywords: Comet Assay; Buccal swab; Hair dyes

The evaluation of formaldehyde (FD) exposure in beauty salons, due to the use hair straightening products, and its relation with genotoxicity biomarkers was performed this study. Regardless official recommendations, inappropriate homemade creams has became a popular practice Brazil, high content "progressive straightening" can contain mutagens that could increase incidence neoplasia those people who them. Damage DNA assessed by conducting micronuclei test (MNT) on buccal cells comet assay heparinized venous blood samples. A total 50 volunteers were recruited at six different salons (labeled F). At two used products did not FD (salons D E), environmental concentrations 0.04 0.02 ppm. In contrast, A, B, C, F contained 5.7, 2.61, 5.9, 5.79% FD, these had 0.07, 0.14, 0.16, 0.14 ppm, respectively. Comparison salon workers from each revealed significant differences urinary formic acid (FA) concentration before (p = 0.016), FA after 0.004), variation 0.018), < 0.001), cytogenetic damage detected according both index 0.001) frequency for karyorrhexis only MNT 0.001).