Efficient preparation of trans-α,β-unsaturated aldehydes from saturated aldehydes by oxidative enamine catalysis

• DOI: 10.1007/s11426-011-4432-6
• Publication Date: 2011-11-13T21:32:16Z
• Authors: ShiLei Zhang; HeXin Xie; AiGuo Song; DeYan Wu; Jin Zhu; SiHan Zhao; Jian Li; XinHong Yu; Wei Wang
• Keywords: Enamine; Iminium

A mild and highly efficient amine-catalyzed, IBX-mediated oxidation of aldehydes to (E) selective α,β-unsaturated aldehydes has been achieved in good yields. The process features a new oxidation of enamines to iminium ions in a catalytic fashion.