Left atrial strain assessment using cardiac computed tomography in patients with hypertrophic cardiomyopathy

• DOI: 10.1007/s11604-023-01401-6
• Publication Date: 2023-02-22T07:02:56Z
• Authors: Takaaki Hosokawa; Hiroshi Kawakami; Yuki Tanabe; Naoki Fukuyama; Kazuki Yoshida; Kentaro Ohara; Takuya Kitamura; Naoto Kawaguchi; Tomoyuki Kido; Takayuki Nagai; Katsuji Inoue; Osamu Yamaguchi; Teruhito Kido
• Keywords: Strain (injury)

Abstract Purpose To evaluate left atrial (LA) function in patients with hypertrophic cardiomyopathy (HCM) by LA strain assessment using cardiac computed tomography (CT-derived strain). Materials and methods This was a retrospective study of 34 HCM 31 non-HCM who underwent (CT) electrocardiogram-gated mode. CT images were reconstructed every 5% (0–95%) the RR intervals. CT-derived (reservoir [LASr], conduit [LASc], booster pump [LASp]) semi-automatically analyzed dedicated workstation. We also measured volume index (LAVI) ventricular longitudinal (LVLS) for functional parameters to assess relationship strain. Results significantly correlated LAVI: r = − 0.69, p < 0.001 LASr; 0.70, LASp; 0.35, 0.004 LASc. LVLS: 0.62, 0.67, LASc; 0.42, 0.013 LASp. lower than that patients: LASr (20.8 ± 7.6 vs. 31.7 6.1%, 0.001); LASc (7.9 3.4 14.2 5.3%, LASp (12.8 5.7 17.6 4.3%, 0.001). Additionally, showed high reproducibility; inter-observer correlation coefficients 0.94, 0.90, 0.89 LASr, LASc, LASp, respectively. Conclusion is feasible quantitative HCM.