Increased Prostaglandin Response to Oxytocin in Ewes Fed a Diet High in Omega‐6 Polyunsaturated Fatty Acids

• DOI: 10.1007/s11745-012-3745-3
• Publication Date: 2012-12-20T12:00:41Z
• Authors: Catherine E. Gull...; Michael A. Friend; Belinda J. King; Susan M. Robertson; John F. Wilkins; Edward H. Clayton
• Keywords: Lipidology; Silage; Prostaglandin f

Diets high in omega-6 polyunsaturated fatty acids (n-6) are associated with increased prostaglandin F(2α) (PGF(2α)) synthesis cattle, however, the specific effects on potential response to an oxytocin challenge sheep have not been reported. The aim of current study was determine whether oxytocin-stimulated PGF(2α) significantly when ewes were fed a diet n-6 compared control low n-6. Merino x Border Leicester (n = 30) received one two dietary treatments, either (70 % oat grain) or (control diet, 100 cereal/legume silage). Ewes consumed diets for 44 days prior consecutive challenges. Plasma and metabolite (PGFM) concentrations following greater (P < 0.05) diet. A higher availability may lead vivo PGF(2α), further research is required exact mechanisms involved.