Microbiologic features of prosthetic joint infections at a tertiary referral orthopaedic unit

• DOI: 10.1007/s11845-025-03933-4
• Publication Date: 2025-03-13T04:16:57Z
• Authors: Stephen Christoph...; Shane P. Russell; James A. Harty; Padhraig O’Loughlin

Abstract Background Prosthetic joint infections (PJI) are a potential devasting consequence of arthroplasty surgery. Knowledge the causative organism and antimicrobial sensitivity increases eradication success rates for PJI. Aims This study aimed to: 1) Observe PJI microbiome at tertiary referral unit; 2) Make comparison to similar published observations; and; 3) Establish empiric local antibiotic guidelines. Methods All patients with positive tissue cultures PJIs over 4 year period were included. An electronic microbiology laboratory database search was performed identify isolated microorganisms, sensitivities resistances. Time from index procedure onset recorded. The identified compared current literature. Results 86 involving 88 joints 56% ( n = 49) related hip, 42% 37) knee 2% (2) shoulder procedures. Coagulase Negative Staphylococci (CoNS) in 32% cases, Staphylococcus aureus (SA) 23%, Enterococcus species Streptococcus 9.0%. 19% case occurred within 3 months surgery, 17% 3–12 64% after 12 months. varied comparable studies. Conclusion describes contrasting results Empiric guidelines have been established target treatment register has since improve patient outcomes stewardship an era resistance.