Cognitive, Mental Health, Functional, and Quality of Life Outcomes 1 Year After Spontaneous Subarachnoid Hemorrhage: A Prospective Observational Study

• DOI: 10.1007/s12028-023-01895-y
• Publication Date: 2023-12-21T18:02:03Z
• Authors: Verena Rass; Klaus Altmann; Laura Zamarian; Anna Lindner; Mario Kofler; Max Gaasch; Bogdan-Andrei Ianosi; Lauma Putnina; Philipp Kindl; Margarete Delazer; Alois J. Schiefecker; Ronny Beer; Bettina Pfausler; Raimund Helbok
• Keywords: Interquartile range; Depression

Abstract Background Patients with spontaneous subarachnoid hemorrhage (SAH) frequently encounter cognitive dysfunction and mental health issues negative effects on health-related quality of life (HR-QoL). Here, we aimed to describe the prevalence deficits, problems, HR-QoL impairments 1 year after SAH. Methods In this prospective observational study, 177 patients SAH admitted our neurointensive care unit over a time span ten years followed invitation for an in-person 1-year follow-up, including standardized neuropsychological test battery. Mental (anxiety depression) were evaluated using questionnaires (Hospital Anxiety Depression Scale; 36-item Short Form questionnaire). Functional outcome was assessed modified Rankin Scale (mRS) score. Results 54 age (interquartile range 47–62 years) presented median Hunt Hess score 2 1–3) at admission. Most (93%) achieved good functional outcomes (mRS 0–2). Seventy-one percent had deficits in least one domain, memory being most prevalent (51%), by executive functions (36%), visuoconstruction (34%), attention (21%). Even perimesencephalic (18%) or full recovery = 0, 46%) comparable (61% 60%, respectively). Symptoms depression anxiety reported 16% 33% patients, respectively. impaired 37% (55 147). ( p 0.001) < more HR-QoL. Conclusions have These impair patients’ life.