Effects of Heat Stress on Gut Microbiome in Rats

• DOI: 10.1007/s12088-021-00948-0
• Publication Date: 2021-05-29T15:03:28Z
• Authors: Qian Qu; Hua Li; Lin Bai; Shiwei Zhang; Jiaqi Sun; Weijie Lv; Chunxin Ye; Cui Liu; Dayou Shi
• Keywords: Cecum; Gut microbiome

Abstract Gut microbiome, as the largest and most important micro-ecosystem, plays a critical role in health. The purpose of this study was to evaluate whether heat stress modulates composition diversity gut microbiome rats. model prepared rats with heating temperature maintained at 35–38°C. Cecum contents were collected after for 3 h days 1, 7. Total DNA extracted 16 S rRNA sequencing analysis intestinal diversity. showed that group changed. And modulated key phylotypes microbiota level phylum genus. In particular, genus Lactobacillus Bacteroides significantly reduced, whereas Oscillospira Clostridium increased by stress. Meanwhile, under encountered change carbohydrate metabolism, amino acid membrane transport defense against Taken together, structure affected some also altered. We conclude could impact multiple biological functions, via altering microbiome.