Consensus guidelines for diagnosis, treatment and follow-up of patients with pancreatic cancer in Spain

• DOI: 10.1007/s12094-016-1594-x
• Publication Date: 2016-12-19T13:14:41Z
• Authors: M. Hidalgo; R. Álvarez; J. Gallego; C. Guillén-Ponce; B. Laquente; T. Macarulla; A. Muñoz; M. Salgado; R. Vera; J. Adeva; I. Alés; S. Arévalo; J. Blázquez; A. Calsina; A. Carmona; E. de Madaria; R. Díaz; L. Díez; T. Fernández; B. G. de Paredes; M. E. Gallardo; I. González; O. Hernando; P. Jiménez; A. López; C. López; F. López-Ríos; E. Martín; J. Martínez; A. Martínez; J. Montans; R. Pazo; J. C. Plaza; I. Peiró; J. J. Reina; A. Sanjuanbenito; R. Yaya; Alfredo Carrato
• Keywords: Cancer Research; Tratamento; humanos; España; guía; Carcinoma Ductal Pancreático; carcinoma; Guideline; oncología médica; estudios de seguimiento; Medical Oncology; Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans; Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Pancreatic Neoplasms; Special Article; 03 medical and health sciences; 0302 clinical medicine; guías de práctica clínica como asunto; neoplasias pancreáticas; Consensus guidelines, Diagnosis, Pancreatic cancer, Treatment; Guías de Práctica Clínica como Asunto; Diagnosis; Medical Subject Headings::Publication Type::Publication Formats::Guideline; Tratamiento; Humans; Consensus guidelines; Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genetic Code::Reading Frames; àncrees -- Càncer -- Tractament; Carcinoma; Guías; Pancreatic cancer; Humanos; 3. Good health; Cáncer de páncreas; Treatment; Pancreatic Neoplasms; Oncology; Spain; Estudios de Seguimiento; Medical Subject Headings::Diseases::Digestive System Diseases::Pancreatic Diseases::Pancreatic Neoplasms::Carcinoma, Pancreatic Ductal; Practice Guidelines as Topic; Neoplasias Pancreáticas; Carcinoma, Pancreatic Ductal; Follow-Up Studies

The management of patients with pancreatic cancer has advanced over the last few years. We convey a multidisciplinary group of experts in an attempt to stablish practical guidelines for the diagnoses, staging and management of these patients. This paper summarizes the main conclusions of the working group. Patients with suspected pancreatic ductal adenocarcinoma should be rapidly evaluated and referred to high-volume centers. Multidisciplinary supervision is critical for proper diagnoses, staging and to frame a treatment plan. Surgical resection together with chemotherapy offers the highest chance for cure in early stage disease. Patients with advanced disease should be classified in treatment groups to guide systemic treatment. New chemotherapeutic regimens have resulted in improved survival. Symptomatic management is critical in this disease. Enrollment in a clinical trial is, in general, recommended.