Improvement in PET/CT image quality in overweight patients with PSF and TOF

• DOI: 10.1007/s12149-014-0912-z
• Publication Date: 2014-09-25T09:14:03Z
• Authors: Takafumi Taniguchi; Go Akamatsu; Yukiko Kasahara; Katsuhiko Mitsumoto; Shingo Baba; Yuji Tsutsui; Kazuhiko Himuro; Shohei Mikasa; Daisuke Kidera; Masayuki Sasaki
• Keywords: Adult; Aged, 80 and over; Male; Phantoms, Imaging; Middle Aged; Overweight; Models, Biological; Multimodal Imaging; 03 medical and health sciences; 0302 clinical medicine; Radiology Nuclear Medicine and imaging; Fluorodeoxyglucose F18; Positron-Emission Tomography; Humans; Original Article; Female; Radiopharmaceuticals; Tomography, X-Ray Computed; Algorithms; Aged; Retrospective Studies

Abstract Objective The aim of this study was to evaluate the effect point spread function (PSF) and time flight (TOF) on PET/CT images overweight patients in relation iteration number acquisition time. Methods This consisted a phantom clinical study. NEMA IEC body 40 cm diameter large (LG phantom) simulating an patient were used Both phantoms filled with 18 F solution sphere background ratio 4:1. PET data reconstructed baseline ordered-subsets expectation maximization (OSEM) algorithm, OSEM + PSF model, TOF model model. retrospective analysis 66 who underwent F-FDG PET/CT. image quality evaluated using variability (coefficient variance, CV liver ) contrast (CONT HOT SNR). Results In study, LG higher than that phantom. decreased level. information accelerated plateau earlier. best relationship between CONT observed for TOF. combination normal weight while it increased SNR similarly two groups. Conclusion correction improved patients.