Wurzelkulturen als Produktionssystem

• DOI: 10.1007/s12268-019-1073-3
• Publication Date: 2019-06-17T07:02:42Z
• Authors: Michael Wink; Bernhard Wetterauer
• Keywords: 0303 health sciences; 03 medical and health sciences; 3. Good health

A number of plant natural products are of commercial interest for pharmacy, medicine, agriculture, or nutrition. A challenge for biotechnology is the production of such compounds in vitro. Whereas callus and suspension cultures of plants mostly fail as production systems, differentiated root cultures provide a better platform. We established normal and transformed root cultures of Ophiorrhiza mungos, which produce the anticancer drug camptothecin in yields, which are similar to differentiated plants.