Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol

• DOI: 10.1007/s12272-001-2106-1
• Publication Date: 2008-10-28T06:17:58Z
• Authors: Hyun-Joo Jung; Yun Seon Song; Chang-Jin Lim; Eun-Hee Park
• Keywords: Carrageenan; Anti-inflammatory; Chorioallantoic membrane

Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.