Diverse distribution patterns of segmental longitudinal strain are associated with different clinical features and outcomes in dilated cardiomyopathy

• DOI: 10.1007/s12574-024-00646-y
• Publication Date: 2024-03-07T06:01:52Z
• Authors: Kaoruko Sengoku; Tomohito Ohtani; Yasuharu Takeda; Toshinari Onishi; Fusako Sera; Misato Chimura; Shozo Konishi; Yasuhiro Ichibori; Masayoshi Yamamoto; Tomoko Ishizu; Yoshihiro Seo; Yasushi Sakata
• Keywords: Dilated Cardiomyopathy; Basal (medicine); Log-rank test

Abstract Background Dilated cardiomyopathy (DCM) presents with diverse clinical courses, hardly predictable solely by the left ventricular (LV) ejection fraction (EF). Longitudinal strain (LS) offers distinct information from LVEF and exhibits various distribution patterns. This study aimed to evaluate significance of LS patterns in DCM. Methods We studied 139 patients DCM (LVEF ≤ 35%) who were admitted for heart failure (HF). was assessed using a bull’s eye map relative apical index (RapLSI), calculated dividing sum basal mid-LS values. evaluated associations cardiac events (cardiac death, LV assist device implantation, or HF hospitalization) reverse remodeling (LVRR), as indicated subsequent changes. Results Twenty six (19%) 29 (21%) exhibited pattern relatively impaired preserved (defined RapLSI < 0.25 > 0.75, signifying 50% decrease increase compared other segments), remaining scattered/homogeneously pattern. The proportion new-onset differed between three groups. During median 595-day follow-up, relatively-impaired had higher rate (both log-rank p 0.05) lower incidence LVRR 0.01) significantly associated event rates after adjusting age, sex, global LS. Conclusion reduced EF experienced different outcomes.