Association between the angiotensin I-converting enzyme gene insertion/deletion polymorphism and endurance running speed in Japanese runners

• DOI: 10.1007/s12576-010-0100-4
• Publication Date: 2010-06-23T06:27:28Z
• Authors: Takuro Tobina; Ryoma Michishita; Fumihiro Yamasawa; Bo Zhang; Hideo Sasaki; Hiroaki Tanaka; Keijiro Saku; Akira Kiyonaga
• Keywords: Endurance Training

We investigated the association between angiotensin I-converting enzyme (ACE) gene insertion (I)/deletion (D) polymorphism and endurance running performance in Japanese elite runners, including several Olympic athletes. The frequency of I/I genotype was not significantly higher D/D lower runners compared with non-athletes. However, I/D tended to be than best for those genotype, average speed combined + genotypes genotype. There were no among five fastest marathon runners. These results suggest that D allele ACE is associated a high level human endurance.