Role of heart rate and stroke volume during muscle metaboreflex-induced cardiac output increase: differences between activation during and after exercise

• DOI: 10.1007/s12576-011-0163-x
• Publication Date: 2011-07-27T07:05:54Z
• Authors: Antonio Crisafulli; Francesco Piras; Michele Filippi; Carlo Piredda; Paolo Chiappori; Franco Melis; Raffaele Milia; Filippo Tocco; Alberto Concu
• Keywords: Adult; Male; 0301 basic medicine; Physiology; Hemodynamics; Blood Pressure; Stroke Volume; Middle Aged; 03 medical and health sciences; Heart Rate; Reflex; Humans; Muscle, Skeletal; Exercise

We hypothesized that the role of stroke volume (SV) in metaboreflex-induced cardiac output (CO) increase was blunted when metaboreflex stimulated by exercise muscle ischemia (EMI) compared with post-exercise (PEMI), because during EMI heart rate (HR) increases and limits diastolic filling. Twelve healthy volunteers were recruited their hemodynamic responses to evoked EMI, PEMI, a control dynamic assessed. The main finding blood pressure increment very similar PEMI settings. In both conditions mechanism used raise CO elevation. However, test increased as result HR elevation whereas an SV. These results explainable on basis different behavior between two settings, which turn led time myocardial performance.