An overview of concepts and approaches used in estimating the burden of congenital disorders globally

• DOI: 10.1007/s12687-017-0335-3
• Publication Date: 2017-10-11T07:57:46Z
• Authors: Sowmiya Moorthie; Hannah Blencowe; Matthew W. Darlison; Joy E. Lawn; Pierpaolo Mastroi...; Joan K. Morris; Bernadette Modell
• Keywords: Public health; Epidemiology; Congenital disorders; Environmental and Occupational Health; 610; name=Epidemiology; /dk/atira/pure/subjectarea/asjc/2700/2716; /dk/atira/pure/subjectarea/asjc/2700/2739; 3. Good health; 03 medical and health sciences; Policy; 0302 clinical medicine; name=Genetics(clinical); name=Public Health; /dk/atira/pure/subjectarea/asjc/2700/2713; Original Article; Public Health

Congenital disorders are an important cause of pregnancy loss, premature death and life-long disability. A range interventions can greatly reduce their burden, but the absence local epidemiological data on prevalence impact impede policy service development in many countries. In attempt to overcome these deficiencies, we have developed a tool-The Modell Global Database Disorders (MGDb) that combines general biological principles available observational with demographic data, generate estimates birth effects mortality disability due congenital disorders. MGDb aims support by generating country, regional global estimates. Here provide overview concepts methodological approach used develop MGDb.