Prevalence rates of mucopolysaccharidoses in Poland

• DOI: 10.1007/s13353-014-0262-5
• Publication Date: 2014-12-03T09:23:47Z
• Authors: Agnieszka Jurecka; Agnieszka Ługowska; Adam Golda; Barbara Czartoryska; Anna Tylki-Szymańska
• Keywords: Mucopolysaccharidosis; Prevalence

The aim of this study was to determine the prevalence rates mucopolysaccharidoses in Poland and compare them with other European countries. A retrospective epidemiological survey covering period between 1970 2010 implemented. Multiple ascertainment sources were used identify affected patients. overall Polish population 1.81 per 100,000. Five different diagnosed a total 392 individuals. MPS III most frequent mucopolysaccharidosis, birth 0.86 100,000 live births. approximately 0.22 cases births obtained for I. For II, estimated as 0.45 births; IV B 0.14 that VI 0.03 1. pattern mucopolysaccharidosis is lower when compared reported countries, such Netherlands, Czech Republic, or Germany, but similar countries like Sweden Denmark. 2. Different frequencies various forms observed. 3. In case VI, incidence values lowest all studies previously published so far.