Combined Bacterial Meningitis and Infective Endocarditis: When Should We Search for the Other When Either One is Diagnosed?
Infective Endocarditis
DOI:
10.1007/s40121-022-00651-7
Publication Date:
2022-05-26T21:02:41Z
AUTHORS (462)
ABSTRACT
We aimed to describe patients with coexisting infective endocarditis (IE) and bacterial meningitis (BM). merged two large prospective cohorts, an IE cohort a BM cohort, only cases of definite community-acquired meningitis. compared who had concurrently only. Among the 1030 included patients, we identified 42 IE–BM (4.1%). Baseline characteristics were mostly similar those IE, but was predominant presentation at admission (39/42, 92.3%). Causative pathogens predominantly Streptococcus pneumoniae (18/42, 42.9%) Staphylococcus aureus (14/42, 33.3%). All pneumococcal associated (18/18). due oral group D streptococci, agalactiae, S. frequently (14/30, 46.7%). Three-month mortality 28.6% in IE–BM, 20.5% 16.6% BM. Patients or altered mental status during must be investigated for aureus, streptococcal enterococcal BM, unfavorable outcome would benefit from echocardiography. dual infection have worst prognosis. Their identification is mandatory initiate appropriate treatment.
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