Assessment of renal impairment using estimated glomerular filtration rate among type 2 diabetes mellitus patients in North-East Ethiopia: a cross-sectional study

• DOI: 10.1007/s40200-020-00680-4
• Publication Date: 2020-11-05T07:02:29Z
• Authors: Mitku Mammo Tader...
• Keywords: Cross-sectional study

Chronic kidney disease (CKD) is the known cause of morbidity and mortality among diabetes mellitus (DM) patients. Targeted screening renal impairment based on estimated glomerular filtration rate (eGFR) DM patients has potential benefits in early identification treatment CKD. Hence, this study was aimed to estimate magnitude using eGFR type 2 patients.An institution-based cross-sectional conducted from February-1 April 30/2020 422 Northeast Ethiopia. Data were collected by semi-structured questioner serum creatinine measurement. The data edited into Epi-data manager version 4.4.1.0, analysis performed SPSS-25. Simplified Modification Diet Renal Disease (MDRD), Kidney Epidemiology (CKD-EPI), Cockcroft-Gault (C-G) equations used calculate eGFR.Of all participants, 82(19.4%), 92(21.8%), 103(24.4%) had < 60 ml/min/1.73 m2, according MDRD, CKD-EPI, C-G equations, respectively. Female sex, (MDRD:AOR = 4.44, 95%CI:1.97-9.97, CKD-EPI:AOR 3.17, 95%CI:1.27-6.17, C-G:AOR 2.65, 95%CI:1.35-5.21), duration ≥ 10 years 3.38, 95%CI:1.45-7.92, 3.09, 95%CI:1.07-7.77, 2.92, 95%CI:1.29-6.61), age ˃60 2.29, 95%CI:1.09-4.77, 4.12, 95%CI:1.68-6.78, C-G: AOR 3.42, 95%CI:1.77-6.60), hypertension 3.12, 95%CI:1.51-6.45, CKD-EPI: 4.21,95%CI:2.07-7.98, 3.99, 95%CI:2.08-7.65), poor glycemic control 2.82, 95%CI:1.13-7.05, 2.34, 95%CI:1.09-5.04), body mass index 1.11, 95%CI:1.01-1.22, 2.43, 95%CI:1.27-5.76) significantly associated with impairment.Renal prevalent Older age, female duration, hypertension, control, BMI impairment.