A Head-On Comparison of EQ-VT- and Crosswalk-Based EQ-5D-5L Value Sets

• DOI: 10.1007/s40258-025-00954-z
• Publication Date: 2025-03-11T19:08:12Z
• Authors: Henry Bailey; Bram Roudijk
• Keywords: Schema crosswalk; EQ-5D; Health Economics; Health administration; Value (mathematics)

No systematic country-level comparison has been undertaken between crosswalk- and EQ-VT-derived EQ-5D-5L value sets. Crosswalk values can differ from EQ-VT-based sets owing to valuation protocols, changes in societal preferences over time, a change the label of highest level on mobility moving EQ-5D-3L EQ-5D-5L. This study aimed compare five-level (5L) crosswalk EQ-VT explore differences them at country level. From countries with both time trade-off (TTO)- or discrete choice experiment (DCE) + TTO-based sets, 19 pairs EQ-5D-3L/EQ-5D-5L were found. For each these 5L developed compared corresponding national set using correlation analysis, ranges, specific states, Bland–Altman plots, scatter plots. Three have data for same respondents. These three cases analyzed separately, as they provide "true" test two Spearman ranged 0.831 0.989, being below 0.9 11 The difference percentage negative +22.5 −18.8%, ranges within pair +42.7 −18.4%. average mean absolute (crosswalk versus EQ-VT) was 0.149. 0.1 only 5 EQ-VT/crosswalk pairs. states comprising one four 1s, no preserved its ranking importance five dimensions values. Most plots scatterplots revealed pattern that placed separate band other states. All criteria showed poor agreement labels most extreme response option dimension leads substantial should not be used interchangeably, except under circumstances where it is possible feasible conduct direct study.