Objective measurement of gait parameters in healthy and cognitively impaired elderly using the dual-task paradigm

• DOI: 10.1007/s40520-016-0703-6
• Publication Date: 2017-01-27T07:05:53Z
• Authors: Alexandra König; Laura Klaming; Marten Pijl; Alexandre Demeurraux; Renaud David; Philippe Robert
• Keywords: Male; Health Status; [INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL]; 03 medical and health sciences; 0302 clinical medicine; Alzheimer Disease; Accelerometry; Humans; Attention; Cognitive Dysfunction; Motor function; Gait; Aged; Aged, 80 and over; Mild cognitive impairment; Mental Status and Dementia Tests; Actigraphy; Dual-task; Walking Speed; 3. Good health; Accelerometer; Ageing; [INFO.INFO-CL] Computer Science [cs]/Computation and Language [cs.CL]; Case-Control Studies; Alzheimer; Disease Progression; Dementia; Original Article; Female; Geriatrics and Gerontology

The present study explores the differences in gait parameters in elderly subjects with or without cognitive impairment measured by means of ambulatory actigraphy while performing a single and a dual task.Sixty-nine participants of which 23 individuals were diagnosed with Alzheimer's disease (AD), 24 individuals with mild cognitive impairment (MCI), and 22 healthy controls performed a single and dual walking task while wearing a wrist-worn accelerometer. Objective measures of gait features such as walking speed, cadence (i.e., number of steps per minute), and step variance (i.e., variance in time between two consecutive steps) were derived and analyzed.While differences in several gait parameters, namely walking speed, were found between MCI and AD patients, no differences between healthy elderly and MCI patients were found.Walking speed seems to be a gait-related feature that differs significantly between MCI and AD patients and thus could be used as an additional measurement in clinical assessment. However, differences in gait may not be salient enough in the early stages of dementia to be detected by actigraphy. More research comparing different methods to measure gait in early stages of dementia under different dual task conditions is neccessary.