Male reproductive health after 3 months from SARS-CoV-2 infection: a multicentric study

• DOI: 10.1007/s40618-022-01887-3
• Publication Date: 2022-08-09T13:02:41Z
• Authors: D. Paoli; F. Pallotti; A. Anzuini; S. Bianchini; L. Caponecchia; A. Carraro; M. R. Ciardi; F. Faja; C. Fiori; D. Gianfrilli; A. Lenzi; M. Lichtner; I. Marcucci; C. M. Mastroianni; G. Nigro; P. Pasculli; C. Pozza; F. Rizzo; P. Salacone; A. Sebastianelli; F. Lombardo
• Keywords: Semen Analysis

Abstract Purpose While SARS-CoV-2 infection appears not to be clinically evident in the testes, indirect inflammatory effects and fever may impair testicular function. To date, few long-term data of semen parameters impairment after recovery comprehensive andrological evaluation recovered patients has been published. The purpose this study was investigate whether affect male reproductive health. Methods Eighty were recruited three months COVID-19 recovery. They performed physical examination, ultrasound, analysis, sperm DNA integrity (TUNEL), anti-sperm antibodies (ASA) testing, sex hormone profile (Total testosterone, LH, FSH). In addition, all administered International Index Erectile Function questionnaire (IIEF-15). Sperm compared with two age-matched healthy pre-COVID-19 control groups normozoospermic (CTR1) primary infertile (CTR2) subjects. Results Median values from subjects within WHO 2010 fifth percentile. Mean percentage fragmentation (%SDF) 14.1 ± 7.0%. Gelatin Agglutination Test ( GAT ) positive 3.9% blood serum samples, but no plasma sample found. Only five (6.2%) had total testosterone levels below laboratory reference range. bilateral volume 31.5 9.6 ml. dysfunction detected 30% Conclusion Our remark that does seem cause direct damage function, while transient. It is possible counsel couples postpone research parenthood or ART procedures around infection.