Group-Based Trajectory Models to Evaluate the Association of Lipid Testing and Statin Adherence

• DOI: 10.1007/s40801-024-00472-9
• Publication Date: 2024-12-21T12:08:22Z
• Authors: Yun-Yi Pan; Sandeep Devabhakt...; Catherine E. Cooke; Julia F. Slejko
• Keywords: Odds

Performing lipid testing after statin initiation is recommended to monitor response. Inadequate response may indicate non-adherence, which associated with an increased risk of cardiovascular events and costs. Group-based trajectory modeling approach establish probabilistic developmental trajectories adherence, differentiating individuals by their distinct longitudinal medication-taking behaviors. We examined whether adherence among enrolled in a Medicare fee-for-service plan the USA. A retrospective cohort study was conducted using Centers for & Medicaid Chronic Condition Warehouse 5% sample data between 2006 2015. Statin use were identified claims data. The proportion days covered calculated each 30 index date, used estimate probability belonging potential trajectory. In 138,101 initiators, four groups identified. differentiated as "rapid decline" (21.53%), "gradual (10.25%), "decline first then improve later" (26.47%), "high adherence" (41.75%). Compared adherence," initiators who had tests within 360 less likely fall into (adjusted odds ratio: 0.661; 95% confidence interval 0.641–0.683), 0.834; 0.801–0.868), 0.936; 0.910–0.962). Lipid positively greater medication across different present study.