Biological potential of eight medicinal plants collected in the restored landscape after mining in South Kalimantan

• DOI: 10.1007/s42452-024-05824-2
• Publication Date: 2024-06-04T07:05:31Z
• Authors: Hesti Lina Wiraswati; Gita Widya Pradini; Nisa Fauziah; Amila Laelalugina; Annisa Retno Arim...; Supandi Supandi; Reza Abdul Kodir; Dikdik Kurnia; Afiat Berbudi; Achadiyani Achadi...; Ilma Fauziah Ma’ruf
• Keywords: 0303 health sciences; 03 medical and health sciences

Abstract Land restoration is expected to enhance the supply of valuable ecosystem resources such as herbaceous bushes and weeds. This study aimed determine primary phytochemical constituents bioactivities methanol extracts from eight weeds collected a restored post-mining landscape in South Kalimantan, Indonesia. Qualitative analysis showed presence phenolic compounds, flavonoids, tannins, alkaloids, steroids, terpenoids saponins plants. Their antioxidant activity was measured by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay. superoxide dismutase (SOD) also measured. In addition, selected plant were screened against common human pathogens Staphylococcus aureus Candida albicans . Phytochemical that contained all bioactive compounds examined this except one Lycopodium cernuum, which lacked flavonoids alkaloids. Further investigation revealed L. cernuum had promising potential. The Chromolaena odorata (stem) , Trema micrantha, Melastoma malabathricum (flower leaf) Thypa angustifolia exhibited effective antibacterial activity. M. leaf), T. Scleria sumatrensis Breynia cernua (leaf) antifungal has greatest potential since its extract exhibits most potent antioxidant, activities.