Biomaterials-enabled electrical stimulation for tissue healing and regeneration

• DOI: 10.1007/s44258-024-00020-8
• Publication Date: 2024-05-21T04:01:28Z
• Authors: Han-Sem Kim; Tanza Baby; Jung-Hwan Lee; Ueon Sang Shin; Hae-Won Kim
• Keywords: 02 engineering and technology; 0210 nano-technology

Abstract The electrical microenvironment is considered a pivotal determinant in various pathophysiological processes, including tissue homeostasis and wound healing. Consequently, extensive research endeavors have been directed toward applying electricity to cells tissues through external force devices or biomaterial-based platforms. In addition situ electroconductive matrices, new class of electroactive biomaterials responsive stimuli has emerged as focal point interest. These materials, response intrinsic biochemical (e.g., glucose) physical light, magnetism, stress), hold significant potential for cell stimulation regeneration. this communication, we underscore distinct category biomaterials, discussing the currently developed biomaterial platforms their biological roles stimulating during healing regeneration process. We also critically evaluate inherent limitations challenges these while offering forward-looking insights into promise future clinical translations. Graphical