Papillary muscle rupture associated to essential thrombocytosis

• DOI: 10.1016/j.ajem.2014.04.038
• Publication Date: 2014-04-26T15:00:47Z
• Authors: Gustavo Avegliano; Diego Conde; Luciano Battioni; Paola Kuschnir; Florencia Castro; Ricardo Ronderos
• Keywords: Thrombocytosis; Chronic myelogenous leukemia; Metaplasia; Myeloproliferative Disorders

Essential thrombocytosis (ET) falls under the umbrella of myeloproliferative disorders, which also includes chronic myelogenous leukemia, polycythemia vera, and myelofibrosis with myeloid metaplasia. Essential thrombocytosis results from a clonal proliferation of megakaryocites within the bone marrow, leading to an absolute elevation of platelets that can cause both hemorrhagic and thrombotic complications.