Menorrhagia I: measured blood loss, clinical features, and outcome in women with heavy periods: a survey with follow-up data

• DOI: 10.1016/j.ajog.2003.11.015
• Publication Date: 2004-05-29T11:05:44Z
• Authors: Pamela E Warner; Hilary O.D Critchley; Mary Ann Lumsden; Mary Campbell-Brown; Anne Douglas; Gordon D Murray
• Keywords: Adult; Blood Volume; Hypovolemia; Middle Aged; Health Surveys; Risk Assessment; Severity of Illness Index; Menstruation; 3. Good health; 03 medical and health sciences; Age Distribution; Logistic Models; 0302 clinical medicine; Predictive Value of Tests; Sickness Impact Profile; Surveys and Questionnaires; Prevalence; Humans; Female; Menstrual Hygiene Products; Menorrhagia; Pain Measurement; Probability

Menorrhagia is defined as blood loss of >80 mL, but in routine clinical practice measurement is seldom undertaken. Our aim was to identify the features of the clinical history that best predict menorrhagic blood loss.A questionnaire survey of 952 menstrual complaint referrals at 3 hospital gynecology clinics in Glasgow and Edinburgh included 226 women with putatively heavy periods who also had consented to the measurement of their blood loss.Only 34% (95% CI, 28%-40%) of women had blood loss volume of >80 mL, but the volume was associated with subjective heaviness of period. Logistic regression with ferritin status, clots, and changing rate during full flow correctly predicts a loss of >80 mL for 76% of women (n=161 patients; sensitivity, 60%; specificity, 86%). Diagnosis and treatment of patients seem unrelated to the volume of blood loss.The subjective judgment of the volume of blood loss is better than has been believed. Clinical features can be combined to predict losses of >80 mL.