Effects of Morning Versus Evening Intake of Atorvastatin on Major Cardiac Event and Restenosis Rates in Patients Undergoing First Elective Percutaneous Coronary Intervention

• DOI: 10.1016/j.amjcard.2005.07.107
• Publication Date: 2005-11-09T12:15:49Z
• Authors: Mehmet Ozaydin; Ozkan Dede; Abdullah Dogan; Suleyman M. Aslan; Ahmet Altinbas; Mustafa Ozturk; Ercan Varol; Yasin Turker
• Keywords: Chronotherapy; Male; Coronary Stenosis; Myocardial Infarction; Middle Aged; Lipids; Angina Pectoris; 3. Good health; Coronary Restenosis; 03 medical and health sciences; C-Reactive Protein; Treatment Outcome; 0302 clinical medicine; Heptanoic Acids; Atorvastatin; Humans; Female; Pyrroles; Prospective Studies; Angioplasty, Balloon, Coronary; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Aged

It is not known whether taking atorvastatin in the morning versus in the evening has a different effect on major cardiac event and restenosis rates in patients undergoing percutaneous coronary intervention. Therefore, the aim of the present study was to investigate the effects of morning versus evening intake of atorvastatin on major cardiac events and restenosis rates and also on serum lipid and high sensitivity C-reactive protein levels in patients with single-vessel disease who underwent first elective percutaneous coronary intervention.