Impact of Aortic Stiffness on Cardiovascular Disease in Patients With Chest Pain<xref ref-type="author-notes" rid="fn1">^*</xref><subtitle>Assessment With Direct Intra-Arterial Measurement</subtitle>

• DOI: 10.1016/j.amjhyper.2007.07.004
• Publication Date: 2017-05-09T14:57:35Z
• Authors: Cheol Ung Choi; Eun Bum Park; Soon Yong Suh; Jin Won Kim; Eung Ju Kim; Seung‐Woon Rha; Hong Seog Seo; Dong Joo Oh; Chang Gyu Park
• Keywords: Stroke

Aortic stiffness is an independent risk factor for cardiovascular (CV) events and mortality. However, there are few studies about the predictive role of aortic stiffness. We investigated association between pulse-wave velocity (aPWV), using direct intra-arterial measurement future CV events, in patients with chest pain. was measured through aorto-femoral, fluid-filled system at baseline 1004 Among these patients, 497 (237 male) were enrolled study. examined tertiles. Tertiles defined as follows: tertile 1, <9.20 m/sec; 2, 9.21 to 12.49 3, >12.50 m/sec. The impact aPWV on newly developed coronary artery disease (CAD), stroke, congestive heart failure evaluated. A higher associated new (odds ratio, 2.18 3 v 1; 95% confidence interval [CI], 1.32 3.60) CAD 1.87 CI, 1.10 3.18) univariate analysis. In multivariate analysis, 2.05 1.18 3.55) 1.86 1.03 3.35). not either stroke (P = .096) or .63). These results suggest that Am J Hypertens 2007;20: 1163–1169 © 2007 American Journal Hypertension, Ltd.