Role of serum C-reactive protein (CRP)/Albumin ratio in predicting the severity of acute pancreatitis: A retrospective cohort

• DOI: 10.1016/j.amsu.2022.104715
• Publication Date: 2022-09-21T14:02:41Z
• Authors: Syed Jawad Haider...; Muhammad Talha Zafar; Beenish Fatima Zia; Saleha Rashid Khalid; Vikesh Kumar; Shaesta Tabassum; Ahmed Ali; Nouman Aziz; Noman Ahmed Khan; Kanchan Kumari; Kanza Saleem; Muhammad Sohaib A...
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Cohort Study; 3. Good health

Acute pancreatitis is a disease with wide spectrum of severity, complications, and outcome severe life-threatening complications develop in patients leading to high mortality acute pancreatitis. The rationale this study diagnose the severity using single test ratio, i.e., CRP/albumin ratio which combination markers for systemic inflammation nutritional status. All those age group 16-80 years who were diagnosed admitted subsequently ICU included. Severe was determined as CT score above 7. About 41% out total 225 had >4.35 sensitivity 87% accuracy 76% predict Elevated also associated like multi-organ failure OR: 2.31 [1.3-4.2], duodenal thickening 2.25 [1.2-4.2], ascites 2.90 [1.5-5.6]. Although, elevation varied different groups, such non-invasive readily available parameters should be relied upon admission risk stratify suffering from has higher negative predictive value than CRP alone hence give additional advantage prognostic marker, although Delong's compare AUROC indifferent (P-value: 0.22).