Myokine interleukin-15 expression profile is different in suckling and weaning piglets

• DOI: 10.1016/j.aninu.2015.02.005
• Publication Date: 2015-03-18T21:19:03Z
• Authors: Yehui Duan; Fengna Li; Bie Tan; Binbin Lin; Xiangfeng Kong; Yinghui Li; Yulong Yin
• Keywords: Litter

Interleukin-15 (IL-15) is a cytokine highly expressed in skeletal muscle. The objective of the present study was to investigate development muscle IL-15 expression suckling piglets and early weaning (day 14) at each level, that is, mRNA, protein, secretion. Eight litters (eight per litter) newborn healthy (Large × White Landrace) with similar initial weight (1618.0 ± 140.1 g) were chosen divided into two groups. Group one used killed, respectively, days 1, 7, 14, 21, group killed 15, 17, 19, 21. In one, gene levels increased significantly (P < 0.05) along body over time. protein day 21 age higher than those other ages, there no difference > among ages. These findings indicated mRNA did not result corresponding increase its expression. two, which from 15-19, constantly piglets. Moreover, gain compared 14 age. However, dropped as age, while markedly both groups, serum decreased 0.01) Taken together, our results indicate differs It speculated may play an important role counteracting effects stress.