The effects of dietary tributyrin on growth, intestinal health, inflammatory response and antioxidant status in juvenile yellow catfish (Pelteobagrus fulvidraco)

• DOI: 10.1016/j.aqrep.2022.101370
• Publication Date: 2022-10-11T15:56:31Z
• Authors: Hongxia Zhao; Dongqiang Hou; Peijia Li; Min Li; Bing Chen; Xifeng Zhu; Junming Cao
• Keywords: Tributyrin; Malondialdehyde; Intraperitoneal injection

The effects of dietary tributyrin (TB) on growth, intestinal health, inflammatory response and antioxidant status in juvenile Pelteobagrus fulvidraco were investigated. fish (initial weight 5.53 ± 0.02 g) fed with diets containing 0 (control, TB0), 500 (TB1), 1000 (TB2) 2000 (TB3) mg/kg for 56 days. results showed that significantly higher final weight, specific growth rate, protein efficiency ratio retention observed TB2 diet compared those TB0 (P < 0.05). Significantly lipid retention, whole-body fat content, intraperitoneal index intestine length found than TB3 Intestinal length, villus muscular thickness, intestosomatic activities trypsin, lipase, alkaline phosphatase, Na+/K+-ATPase TB1 or had lower interleukin-1β, interleukin-6, tumou necrosis factor-α, malondialdehyde contents hepatic glutathione, superoxide dismutase Compared TB0, the relative expressions claudin-1, zomula occludens protein-1, occludin, lipoprotein lipase fatty acid synthase increased TB1, Together, TB improved deposition, but decreased response, probably through modulating tight junction proteins metabolism related genes expression activating system.