Transapical Transcatheter Mitral Valve-in-Valve Implantation in a Human

• DOI: 10.1016/j.athoracsur.2008.10.016
• Publication Date: 2009-02-25T04:59:34Z
• Authors: Anson Cheung; John G. Webb; Daniel R. Wong; Jian Ye; Jean-Bernard Masson; Ronald G. Carere; Samuel V. Lichten...
• Keywords: Bioprosthesis; Heart Valve Prosthesis Implantation; Male; Cardiac Catheterization; Prosthesis Design; 3. Good health; 03 medical and health sciences; Fatal Outcome; 0302 clinical medicine; Heart Valve Prosthesis; Humans; Mitral Valve; Mitral Valve Stenosis; Aged

We describe a human transcatheter transapical mitral valve implant within a mitral bioprosthesis (valve-in-valve). A high-risk, 80-year-old man with symptomatic bioprosthetic mitral stenosis was positioned for anterior minithoracotomy. Left ventricular apical access was obtained. After balloon valvuloplasty, a cuffed, 26-mm Cribier-Edwards transcatheter valve (Edwards Lifesciences LLC, Irvine, CA) was deployed within the mitral xenograft, using rapid ventricular pacing. The transcatheter valve functioned properly postoperatively; however, the patient died of multiple organ dysfunction.