The long-term exercise after traumatic brain injury: Reharmonizing brain by sound body

• DOI: 10.1016/j.brainres.2023.148471
• Publication Date: 2023-06-24T14:01:32Z
• Authors: Roozbe Bonsale; Rosmara Infantino; Michela Perrone; Ida Marabese; Federica Ricciardi; Antimo Fusco; Milena Melake Tew...; Serena Boccella; Francesca Guida; Barbara Rinaldi
• Keywords: Neurochemical; Depression

Traumatic brain injuries (TBI) refer to multiple acquired dysfunctions arising from damage the caused by an external force, including rapid acceleration/deceleration and concussion. Among them, mild TBI (mTBI) accounts for most cases (up 90%) of injuries. It is responsible a variety symptoms, anxiety, depression, cognitive impairments that remain difficult be treated. has been reported regular physical activity, as well as, improving life quality, display neuroprotective function, suggesting possible role in post-traumatic rehabilitation. In this study, we investigated effects treadmill exercise mice mTBI model behavioural, electrophysiological neurochemical analysis. Daily decreased aggressive behavior, depression mice. Accordingly, maladaptive rearrangement occurring hippocampus were prevented exercise.