Resting-state background features demonstrate multidien cycles in long-term EEG device recordings

• DOI: 10.1016/j.brs.2023.11.005
• Publication Date: 2023-11-16T22:47:48Z
• Authors: William K.S. Ojemann; Brittany H. Scheid; Sofia Mouchtaris; Alfredo Lucas; Joshua J. LaRocque; Carlos Aguila; Arian Ashourvan; Lorenzo Caciagli; Kathryn A. Davis; Erin C. Conrad; Brian Litt
• Keywords: Epilepsy; Interictal; Spikes; Neurosciences. Biological psychiatry. Neuropsychiatry; RNS; Neurostimulation; Biomarkers; Article; 3. Good health; RC321-571

Longitudinal EEG recorded by implanted devices is critical for understanding and managing epilepsy. Recent research reports patient-specific, multi-day cycles in device-detected epileptiform events that coincide with increased likelihood of clinical seizures. Understanding these could elucidate mechanisms generating seizures advance drug neurostimulation therapies.